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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Study period:
2014
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: This study is classified as reliable with restrictions because it is an acceptable and reliable study carried out by OECD ToolBox v.3.2.0. Meets generally accepted scientific principles, acceptable for assessment.

Data source

Reference
Reference Type:
other: software
Title:
QSAR ToolBox 3.2.0.103
Author:
OECD
Year:
2014
Bibliographic source:
http://www.oecd.org/env/ehs/risk-assessment/theoecdqsartoolbox.htm

Materials and methods

Principles of method if other than guideline:
Read-across from category members
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
2668-75-9
EC Number:
607-988-8
Cas Number:
2668-75-9
IUPAC Name:
2668-75-9
Constituent 2
Reference substance name:
66212-25-7
EC Number:
613-906-1
Cas Number:
66212-25-7
IUPAC Name:
66212-25-7
Constituent 3
Reference substance name:
17183-98-1
EC Number:
605-617-4
Cas Number:
17183-98-1
IUPAC Name:
17183-98-1
Constituent 4
Reference substance name:
17β-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one
EC Number:
259-701-7
EC Name:
17β-hydroxy-17-(3-hydroxypropyl)androst-4-ene-4-one
Cas Number:
55542-27-3
IUPAC Name:
55542-27-3
Constituent 5
Reference substance name:
17β-hydroxy-17-(3-hydroxy-1-propynyl)androst-4-ene-3-one
EC Number:
259-700-1
EC Name:
17β-hydroxy-17-(3-hydroxy-1-propynyl)androst-4-ene-3-one
Cas Number:
55542-26-2
IUPAC Name:
17-hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)

Results and discussion

% Degradation
Parameter:
other: average value from the 5 nearest neighbours
Value:
36.5
St. dev.:
46.2
Remarks on result:
other: Read-across from category members
Details on results:
The prediction is based on 5 values within the range 1.00 - 82.0, %
Prediction confidence = ± 46.2, % (95.0%)

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
not inherently biodegradable
Conclusions:
Not Ready Biodegradable