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EC number: 205-117-2 | CAS number: 133-66-4
Well defined erythema (grade 2) was observed in all animals after 24 hours, as well as in 4/6 animals at 48 and 72 hours. After 24, 48 and 72 hours, the erythema scores were 2.0, 1.7 and 1.7, respectively (intact skin). Except for one slight edema (grade 2) in one male after 48 hours, only very slight edema (grade 1) was observed in some animals after 24, 48 and 72 hours. After 24, 48 and 72 hours, the edema scores were 1.0, 0.7 and 0.5, respectively (intact skin). The total of all scores, i.e. for intact AND abraded skin, was 9.3. The primary irritation index (for abraded AND intact skin) was 2.33, which was listed as being in the moderate range (2.1-4.0). All effects were fully reversible within 7 days (all scores: 0.0). There was no staining of the treated skin.
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