Registration Dossier
Registration Dossier
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EC number: 204-594-4 | CAS number: 123-04-6
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
The substance is moderately biodegradable (OECD 310; 43% after 60 d; BASF SE, 2011, report no. 27G0397/11G065). QSAR data are conflicting regarding ready biodegradability. The BIOWIN model does not indicate persistence. The CATALOGIC model also indicates that the substance is not readily biodegradable (40% after 28 d), while the resulting metabolites are readily biodegradable (BOD > 60%; CATALOGIC v5.11.5TB BOD 28 days MITI (OECD 301C) v06.07). Therefore it can be concluded that the substance is not readily biodegradable, but persistence is not indicated.
The substance has a log Kow of 5.6 (measured), an experimentally determined BCF is not available. Therefore accumulation of 3-(chloromethyl)heptane is possible (log Kow >4). According to the CATALOGIC model (v5.11.5TB BOD 28 days MITI (OECD 301C) v06.07), the substance's metabolites are not expected to accumulate significantly in organisms due to a log Kow < 4 and their ready biodegradability. This is supported by the BCFBAF model (v3.01; Arnot-Gobas BCF Methods including a biotransformation rate estimates, T1/2 4.15 d), which results in a BCF of < 2000 for the upper trophic level. In conclusion the substance is not B or vB.
The substance is not T. Chronic toxicity data are only available for algae, but not for fish and Daphnia. The lowest acute value is greater than 0.1 mg/L (Daphnia, 48-h EC50 = 0.375 mg/L, BASF SE, 2012, report no. 50E0397/11E107). The only available chronic value (algae) is greater than 0.01 mg/L (algae: 72-h ErC10 = 0.424 mg/L; BASF SE, 2012, report no. 60E0397/11E106). The substance holds no relevant classification.
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