Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.16
Temp.:
23 °C
pH:
ca. 2.4
Details on results:
Results in detail:

determ. no. stock solution n-octanol test substance test substance
conc. in n-octanol conc. in water
[ml] [ml] phase [mg/l] phase [mg/l] Log Pow
A1 5 10 119,6 157,4 - 0,12
A2 5 10 122,8 157,1 - 0,11
B1 10 10 155,8 229,2 -0,17
B2 10 10 152,7 219,7 -0,16
C1 20 10 181,5 293,0 -0,21
C2 20 10 188,5 291,0 -0,19
mean -0.16

Any other information on results incl. tables

Recovery rate: 96 - 104 %

pH of aqueous solution : 5.9 - 7.2

Applicant's summary and conclusion

Conclusions:
The Log Pow of the substance is -01,6 at 23°C.
Executive summary:

The Partition Coefficient n-octanol/water of the substance was determined according to OECD guideline 107 with shake flask method and was found to be -0,16 at 23°C