Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Several in vitro and in vivo genotoxicity studies were performed with thioglycolic acid and its salts. The conducted genotoxicity studies on thioglycolic acid or its salts described in this chapter can be bridged to each other, because in aquous solutions only the organic thioglycolate anion may have the potential to cause genotoxic effects in vitro or in vivo. All genotoxicity studies conducted to date have either negative results or are of douptful significance. Therefore, the weight of evidence suggests that thioglycolic acid and its salts are non-genotoxic.


Short description of key information:
The weight of evidence suggests that CaTG is not genotoxic.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Conclusive, but not sufficient for classification.