Registration Dossier
Registration Dossier
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EC number: 203-057-1 | CAS number: 102-81-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not expected when introduced in appropriately low concentrations.
Key value for chemical safety assessment
Additional information
The assessment of the toxicity of Dibutylethanolamine (DBEA; CAS 102 -81 -8) to aquatic microorganisms is based on experimental data from a respiration inhibition test according to OECD 209, performed under GLP-conditions (BASF SE 2005, report no. 08G03286/053095). Non-adapted activated sludge from a municipal wastewater treatment was used as inoculum. The pH of the test solutions was adjusted. The 30 -min EC20 was determined to be greater than 1000 mg/L, based on nominal concentrations, indicating that no effect on the degradation activity is anticipated for activated sludge if DBEA is introduced in appropriately low concentrations.
The data for the key study are supported by the results of a non-GLP study conducted according to OECD 209 (BASF AG 1985, report no. 1120). Activated slugde from an industrial wastewater treatment plant was used as inoculum. The 30 -min EC20 was determined to be > 1000 mg/L (nominal).
In both studies, the concentrations were not analytically verified during the test. However, DBEA proved to be stable in other studies (e.g. see IUCLID Chapters 6.1.3 or 6.1.5); in addition, the stubstance is assumed to be stable due to the substances' water solubility is 4000 mg/L (BASF SE 2012, report no. 11L00536), its moderate vapor pressure (VP = 0.05 hPa @20°C, BASF SE 2012, report no. 11L00536) and its low Henry's Law Constant (HLC = 0.217 Pa m³/mol, calculated with the VP/WS method, BASF SE 2017).
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