Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bioaccumulation by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
Name of test material: 5-hydroxyisopthalic acid
Molecular formula:C8H6O5
Substance type: Organic

Test organisms

Test organisms (species):
other: Fish

Study design

Route of exposure:
aqueous
Test type:
other: estimated values
Water / sediment media type:
not specified

Test conditions

Hardness:
Not reported
Test temperature:
Not reported
pH:
Not reported
Dissolved oxygen:
Not reported
TOC:
Not reported
Salinity:
Not reported

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.2
Basis:
not specified
Calculation basis:
other: estimated
Remarks on result:
other: other details not available

Applicant's summary and conclusion

Conclusions:
The estimated bioconcentration factor (BCF) for 5-hydroxyisopthalic acid is 3.2, does not exceed the bioconcentration threshold of 1000. Thus it is concluded that 5-hydroxyisopthalic acid is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Executive summary:

The estimated bioconcentration factor (BCF) for 5-hydroxyisopthalic acid is 3.2, does not exceed the bioconcentration threshold of 1000. Thus it is concluded that 5-hydroxyisopthalic acid is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.