Registration Dossier

Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

Administrative data

Endpoint:
biodegradation in water and sediment: simulation tests
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Biodegradation in water and sediment by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Modelling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name of test material: 5-hydroxyisopthalic acid
Molecular formula:C8H6O5
Substance type: Organic

Study design

Oxygen conditions:
other: estimated database

Results and discussion

Mean total recoveryopen allclose all
Compartment:
other: water, material (mass) balance
% Recovery:
19
Compartment:
other: sediment, material (mass) balance
% Recovery:
0
% Degradationopen allclose all
% Degr.:
50
Parameter:
test mat. analysis
Sampling time:
360 h
Remarks on result:
other: 15days=360hrs
% Degr.:
50
Parameter:
test mat. analysis
Sampling time:
3 360
Remarks on result:
other: 140days= 3360hrs
Half-life of parent compound / 50% disappearance time (DT50)open allclose all
Compartment:
water
DT50:
15 d
Type:
other: estimated
Remarks on result:
other: other details not available
Compartment:
sediment
DT50:
140 d
Type:
other: estimated
Remarks on result:
other: Other details not available
Transformation products:
not specified

Any other information on results incl. tables

Media

Half-Life 
(days)

Percent in
Each Medium

Water

15

  19%

Sediment

140

  0%

Applicant's summary and conclusion

Conclusions:
Half life period of 5-hydroxyisopthalic acid in water is observed to be 360 hrs (15 days) while in sediment it is 3360 hrs (140 days).Based on these half life values of 5-hydroxyisopthalic acid, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.
Executive summary:

Half life period of 5-hydroxyisopthalic acid in water is observed to be 360 hrs (15 days) while in sediment it is 3360 hrs (140 days).Based on these half life values of 5-hydroxyisopthalic acid, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.