Registration Dossier

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25.10.2012-17.11.2012
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Name of test material: 5-hydroxyisopthalic acid
Molecular formula:C8H6O5
Substance type: Organic

Results and discussion

Partition coefficient
Type:
Pow
Partition coefficient:
2.2
Temp.:
24 °C
pH:
2.94
Remarks on result:
other: relatively hydrophobic

Applicant's summary and conclusion

Conclusions:
The experimental value of octanol water partition co-efficient (log Pow) of 5-hydroxyisopthalic acid is 0.342 at 24 degC and pH of 2.94.
Executive summary:

The experimental value of octanol water partition co-efficient (log Pow) of 5-hydroxyisopthalic acid is 0.342 at 24 degC and pH of 2.94.This value indicates that 5-hydroxyisopthalic acid is relatively Relatively hydrophobic in nature