Acetaldehyde oxime

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.03 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.3 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.003 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

500 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

135 µg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

13.5 µg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

9.38 µg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Conclusion on classification

CLP

 

Acute aquatic hazard:

• Reliable acute toxicity data are available for fish (Buccafusco 1981a, 1981b, Geiger et al., 1990), algae (van Dijk., 2005) and crustacea (Palmieri, 1981). The 48-hour Daphnia magna test resulted in an EC₅₀of 770 mg/L, whereas an E_rC₅₀of 74 mg/L was found in the 72-hour toxicity test on Selenastrum capricornutum. The lowest 96-hour LC₅₀for fish was reported in Bluegill sunfish (Lepomis macrochirus), namely 30 mg/L.
• Based on the fact that the most sensitive species should be taken into account for determination of the aquatic hazard, the classification should be based on the outcome of the fish test. When comparing these test results with the respective criterion (> 10 mg/L), it can be concluded that no classification for Acute Aquatic Toxicity is warranted according to the CLP Regulation (EC) No. 1272/2008 (amended according to Commission Regulation No 286/2011).

 

Chronic aquatic hazard:

• Chronic toxicity data is not available for AAO. 
• Experimental data on biodegradation is available (Stevenson and Blum, 1981). Under standard ready biodegradation test conditions, the test chemical displayed degradation, however the criteria for readily biodegradable were not fulfilled. Therefore, AAO would be regarded as inherently biodegradable rather than readily biodegradable.
• Experimental data on bioaccumulation not available. However, as the log Kow is below 1 and the estimated BCF is 0.5, the low bioaccumulative potential of AAO is sufficiently demonstrated.
• As a consequence of the fact that the substance is not rapidly biodegradable (only inherently) and the absence of adequate chronic toxicity data chronic toxicity will be based upon the results of the acute toxicity data. As the acute toxicity data indicate effect levels of 30 mg/L, it has to be concluded that the substance (AAO) is to be classified as Chronic Category 3.
• An M-factor for chronic toxicity could not be determined as there is no chronic toxicity information.

DSD

 

Acute and chronic aquatic hazard:

• Reliable acute toxicity data are available for fish (Buccafusco 1981a, 1981b, Geiger et al., 1990), algae (van Dijk., 2005) and crustacea (Palmieri, 1981). The 48-hour Daphnia magna test resulted in an EC₅₀of 770 mg/L, whereas an E_rC₅₀of 74 mg/L was found in the 72-hour toxicity test on Selenastrum capricornutum. The lowest 96-hour LC₅₀for fish was reported in Bluegill sunfish (Lepomis macrochirus), namely 30 mg/L.
• Based on the fact that the most sensitive species should be taken into account for determination of the aquatic hazard, the classification should be based on the outcome of the fish test.
• Experimental data on biodegradation is available (Stevenson and Blum, 1981). Under standard ready biodegradation test conditions, the test chemical displayed degradation, however the criteria for readily biodegradable were not fulfilled. Therefore, AAO would be regarded as inherently biodegradable rather than readily biodegradable.
• Experimental data on bioaccumulation not available. However, as the log Kow is below 1 and the estimated BCF is 0.5, the low bioaccumulative potential of AAO is sufficiently demonstrated.

• As a consequence, AAO should be classified as R52/R53 according to the criteria as mentioned in section 5 of Annex VI of Directive 67/548 (Dangerous Substances Directive).