Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according EU/OECD guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
3.6
Temp.:
25 °C
pH:
8.9
Type:
Pow
Partition coefficient:
3 981
Temp.:
25 °C
pH:
6.9

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test item was at 25 °C (pH = 6.0):
log POW 3.6
POW 3981