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EC number: 610-848-9 | CAS number: 52479-58-0
A 90-day repeated dose oral toxicity study is available for the submission substance.
A 90 -day repeated dose oral toxicity study performed with the submission substance (Longobardi, 2017) reports a NOAEL of 275 mg/kg bw/d, based on findings (mortality, clinical signs, changes in haematology and clinical chemistry parameters and increased liver weight at the highest dose level of 750 mg/kg bw/d. A slight reversible increase in liver weight without pathological correlates and minor fluctuations in clinical chemistry parameters seen at 275 mg/kg bw/d were not considered to represent an adverse effect.
No classification is proposed: relevant data are not available
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