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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
The study was conducted between 18 June 2014 and 22 August 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry
Atm. press.:
102.5 kPa
Decomposition:
yes
Decomp. temp.:
250 °C

Thermal Data

Thermographic data for determinations 1 and 2 are shown in the following table.

Thermal Event Interpretation Temperature
Determination 1 Determination 2
°C K °C K
Endotherm Melting 131.9 405 131.7 404.8

Visual Assessment by Metal Block

The temperatures and observations recorded during the metal block assessment are shown in the following table.

Time (mm:ss) Temperature Observations
°C K
00:00 20 293 Test item is a white powder
12:30 131 404 Test item begins to melt
13:00 135 408 Test item has melted into a clear colorless liquid
17:30 160 433 Bubbles forming in the test item
29:00 250 523 Test item is a light brown liquid
32:30 275 548 Test item is a brown liquid
40:00 335 608 Test item is a dark brown liquid
42:50 340 613 Test item is a dark brown/black liquid
44:20 350 623 Test item is a dark brown/black liquid

Discussion

The endotherm observed for the melting temperature gave an onset of approximately 1 °C higher than that determined in Section 3.1. This has been attributed to a measurement lag due to the higher heating rate used in the boiling temperature determination. Due to the low enthalpy change during decomposition it was not possible to determine the exact temperature at which decomposition began. The onset of decomposition has been taken from 250 °C, the temperature where a color change was first noted in the visual assessment.

Conclusions:
The test item has been determined to decompose from 250 °C (523 K). As the test item decomposed, no value for boiling temperature could be determined.
Executive summary:

The general physico-chemical properties of BMS-587172-01 have been determined. The results are summarized below:

Boiling Temperature

Decomposed from 250 °C (523 K) using a metal block method, designed to be compatible with Method A2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The test item has been determined to decompose from 250 °C (523 K). As the test item decomposed, no value for boiling temperature could be determined.

Description of key information

As the test item decomposed, no value for boiling temperature could be determined.

The test item has been determined to decompose from 250 °C (523 K).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
250 °C

Additional information

Decomposed from 250 °C (523 K) using a metal block method, designed to be compatible with Method A2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.