Registration Dossier
Registration Dossier
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EC number: 218-377-7 | CAS number: 2136-89-2
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
Materials and methods
Test material
- Reference substance name:
- α,α,α,2-tetrachlorotoluene
- EC Number:
- 218-377-7
- EC Name:
- α,α,α,2-tetrachlorotoluene
- Cas Number:
- 2136-89-2
- Molecular formula:
- C7H4Cl4
- IUPAC Name:
- 1-chloro-2-(trichloromethyl)benzene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- - Age at study initiation: 8 - 10 weeks
- Weight at study initiation: males: 206 g - 320 g
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- unchanged (no vehicle)
- Duration of exposure:
- 24 hours
- Doses:
- 1000, 2000 mg/kg bw
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
Applicant's summary and conclusion
- Conclusions:
- The LD50 value for acute dermal toxicity is > 2000 mg/kg bw in male/female Sprague-Dawley rats.
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