Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 200-929-3 | CAS number: 76-05-1
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a secondary literature on the effects of anesthetics on reproduction and development in human
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
This review summarized the results of epidemiologic studies that assessed the adverse reproductive and developmental effects of anesthetic exposure on the pregnant surgical patient and the occupationally exposed female and male health care worker.
There is evidence in some of the studies of an increased rate of spontaneous abortion and fetal and perinatal mortality. These associations appear to be dependent on a number of factors that are not uniformly related to anesthesia alone.
But the epidemiologic evidence is too weak to conclude that there is a causal association between anesthetic exposure and adverse reproductive and developmental outcomes.
As this review deals only with anesthetic in a general manner, this publication was not consider in the toxicity assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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