Zinc selenite

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2010-02-04 to 2010-02-11

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

yes

Remarks:

the preliminary was not performed acc. to guideline; deionised water with TOC <1ppm and conductivity below 0.1 µS/cm was used instead of double distilled water.

GLP compliance:

yes (incl. QA statement)

Remarks:

signed 2007-01-12

Type of method:

flask method

Water solubility:

16 mg/L

Temp.:

20 °C

pH:

ca. 6

Details on results:

- after the analysis of the sample flask 1 of day 3, the plateau was considered as reached
- temperature was measured with 20±0.5 °C
- in flask 2-6, a standard deviation of 2.35 mg/L was calculated, giving a relative standard of 15.4 %
- the measurements of day 1 and 2 were also included in the calculation of the mean since the difference between measured concentrations lay below 15 %
- the mean concentration of zinc selenite was calculated to be 16.00 ± 2.03 mg/L

Table 1: Equilibration data

day	flask	T [° C]	pH	Dilution factor	Se conc. [mg/L]	Difference to previous sample	ZnSeO3 conc. [mg/L]
1	1	19.5	6	10	0.711	-	17.33
2	1	20.5	6	10	0.704	-1.0 %	17.16
3	1	20.1	6	10	0.700	-0.7 %	17.05

 

Table 2: Values which were measured in flask 2-6 at the plateau (day 3)

Flask	2	3	4	5	6
pH	7.41	7.05	7.21	7.30	7.60
Se conc. [mg/L] (diluted sample)	0.579	0.749	0.663	0.493	0.654
Dilution factor	10	10	10	10	10
Se conc. [mg/L] (original sample)	5.79	7.49	6.63	4.93	6.54
Factor (content Se/test item)	0.41046	0.41046	0.41046	0.41046	0.41046
Conc. ZnSeO3 [mg/L]	14.11	18.24	16.16	12.00	15.94

 

Table 3: Measurements used for calculation

day	Flask	Mean conc. ZnSeO3 [mg/L]	Total mean [mg/L]	Total standard deviation
1	1	17.33	16.00	2.03 mg/L (12.7 %)
2	1	17.16
3	1	17.05
3	2	14.11
3	3	18.24
3	4	16.16
3	5	12.00
3	6	15.94

 

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
Under the conditions of this flask method, the water solubility of zinc selenite at 20.0 ± 0.5 °C was determined at 16.00 ± 2.03 mg/L. A relative standard deviation of 12.7 % was calculated. The replicates showed good correspondence, and standard deviation, within the sampling days as well as all over the plateau, was satisfying.

Description of key information

Zinc selenite is slightly soluble in water. Under the conditions of the performed flask method, the water solubility of zinc selenite at 20.0 ± 0.5 °C was determined at 16.00 ± 2.03 mg/L.

Key value for chemical safety assessment

Water solubility:

16 mg/L

at the temperature of:

20 °C

Additional information

The test data (GLP, OECD guideline conform) is reliable without restrictions.