Registration Dossier
Registration Dossier
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EC number: 295-322-3 | CAS number: 91995-60-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Data are available for TAME. The 16-h EC10 in Pseudomonas putida is 25 mg/l.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 25 mg/L
Additional information
Based on the considerations described in the document “Read-across substantiation C5-6 branched alkylmethyl-ethers” (incl. the supporting references Tuppurainen et al., 2007 and Niska et al., 2008), it can be concluded that the available information of TAME can be used to predict the toxicity to microorganisms of the substance ‘C5-6 branched alkylmethyl-ethers’ with sufficient certainty.
One study withPseudomonas putidais available for TAME, which is conducted according to ISO 10712, the 16-h EC10 is 25 mg/l (SafePharm Laboratories, 2003c). This value will be used in the assessment since no data are available to support the derivation of a weighted average.
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