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Description of key information

Human data are limited. BF3 could be responsible of irritability, insomnia, headache, excessive fatigue, effects on the respiratory tract.

Additional information

Human data are limited to a few case reports about workers occupationally exposed to boron trifluoride and that were especially discussed in the NIOSH criteria document. In the limitedly reported case study, acid burns were found upon placing cotton soaked with boron trifluoride in water on the skin for some days. According to an abstract of one study, 51 workers exposed to not reported levels unspecified concentrations of boron trifluoride (and other compunds) for 10 to 15 years had experienced irritability, insomnia, headache, excessive fatigue, effects on the respiratory tract (dryness and bleeding of mucosa, bronchitis, emphysema) and the skin (exanthema, dryness), joint pain, and increased fragility of tooth enamel. In the other study, minimally to severely lowered pulmonary function was seen in 8 out of 13 workers with present or past exposure to boron trifluoride and other fluorides for one to 27 years.

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