Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

These results show that the test substance elicits an SI = 3. The EC3 value (the estimated test substance concentration that will give a SI =3) was established to be between 0 and 2.5%.

Migrated from Short description of key information:
An in vivo assessment of contact hypersensitivity to TTP in the mouse (Local Lymph Node Assay) was performed, which showed the test substance to be sensitizing.

Justification for classification or non-classification

Based on these results:

- according to the recommendations made in the test guidelines, TTP would be regarded as skin sensitizer.

- according to the Regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures, TTP should be classified as skin sensitizer (Category 1) and labeled as H317: May cause an allergic skin reaction.

- according to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) of the United Nations (2007), TTP should be classified as skin sensitizer (Category 1).