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Description of key information

LD50 of the test item Methylal is 7.46 ml/kg bw  (6423mg/kg bw) by oral route (gavage) for both male and female rats (Myers, 1982).

Dermal LD50 and Inhalation LC50 were 5000 mg/kg bw and 57000 mg/m³, respectively (Rush, 1989; Weaver, 1951).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
6 423 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
57 000 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
5 000 mg/kg bw

Additional information

Justification for classification or non-classification

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