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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

After 21 days of exposure to 3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate, the 21 days EC10-reproduction and 21 days EC50-reproduction respectively, were 0.84 (calculated value) and >3.11 mg/L (measured value).

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
0.84 mg/L

Additional information

This study was designed to assess the prolonged toxicity of 3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate to Daphnia magna. This was assessed by counts of the numbers of neonates produced during 21 days. It was conducted in compliance with GLP and according to the OECD Guideline for Testing of Chemicals, No. 211 “Daphnia magna, reproduction test” (adopted 3 October 2008).

Since it was not possible to develop a method of analysis with sufficient sensitivity to verify all exposure concentrations employed during the study, samples were only taken for analysis at the highest test level, 3 mg/L. To enable the test results to be expressed as measured concentrations, the concentrations at 0.0286 to 0.938 mg/L have been calculated assuming 104% of their nominal values were present, giving calculated concentrations of 0.0297, 0.0953, 0.305, and 0.976 mg/L. Based on the geometric mean, the measured concentration at 3.0 mg/L was 3.11 mg/L.

After 21 days of exposure, the 21 days EC10-reproduction and 21 days EC50-reproduction respectively, were 0.84 (calculated value) and >3.11 mg/L (measured value).