Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 444-280-6 | CAS number: 7689-03-4
Guidance on Safe Use
Administrative data
First-aid measures
position; if person feels unwell, seek medical advice.
Emergency measure - Eyes: Wash inmediately with plenty of water with open eye at least
for 15 min;seek medical advice immediately.
Emergency measure - Skin: Remove contaminated clothes; wash with plenty water and
soap; seek medical advice, if irritation develops.
Emergency measure - Ingestion: Give affected person 3-4-glasses of water to drink; do not
induce vomiting; if vomitting occures, give water again;
seek medical advice immediately
Fire-fighting measures
materials
Product arising from burning: carbon dioxide, water
Product determined by test: N
Protective equipment: self-contained respiration protection and the common
protection measures for fires with chemicals.
Accidental release measures
protective coverings and gloves. Use HEPA filtered vacuum or
wet sweeping to clean up spillage. Avoid dust. Place
spillage in appropiate container for waste disposal. Wash
contaminated clothing for waste disposal. Wash contaminated
clothing before reuse. Ventilate area and wash spill site.
Handling and storage
Use with adequate dust control and local ventilation.
Avoid contact with eyes, skin and clothing.
Workers should wear gloves and anti-dust masques.
Shower body after handling.
Wear fresh clothes daily.
No special precautions against fire and explosion is require
d.
Storage: Store at room temperature, in original container, protect
from heat and direct sunlight.
Packaging of the substance and or preparation: The substance is packed in steel containers Buck docking
system.
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
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Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
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Special provisions / remarks
- Remarks:
- Transport code: 1544, Solid Alkaloid
Transport: It is clasified as a toxic good and packaging Group I.
Labelling 6.1, II ADR
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Stability and reactivity
Dust explosion: none
Dust explosion determined by test: N
Disposal considerations
intermediate for a chemical reaction.
Industry - Possibility of neutralisation: During semisynthetic or total synthetic chemistry programs
the particular importance of the lactone ring and the 20
(S)-configuration for activity was recognized. With an
alkali solution ( 5% Sodium hydroxide solution ) the
Camptothecin lactone ring is easily hydrolized.
Industry - Possibility of destruction: controlled discharge: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Industry - Possibility of destruction - incineration: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Industry - Possibility of destruction - water purification: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Industry - Possibility of destruction - other: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Public at large - Possibility of recovery/recycling: Does not apply due to the fact that CAMPTOTHECIN is used by
industry in closed systems only.
Public at large - Possibility of neutralisation: With an alkali solution ( 5 % Sodium hydroxide solution )
Public at large - Possibility of destruction: controlled discharge: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Public at large - Possibility of destruction - incineration: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Public at large - Possibility of destruction - water purification: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Public at large - Possibility of destruction - others: Does not apply due to the fact that CAMPTOTHECIN is an
intermediate for a chemical reaction.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
