Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
other:
Title:
Unnamed
Year:
1992

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
other:

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
conjunctivae score
Basis:
animal #1
Time point:
other:
Score:
1
Remarks on result:
other:
Irritation parameter:
conjunctivae score
Basis:
animal #2
Time point:
other:
Score:
0.7
Remarks on result:
other:
Irritation parameter:
conjunctivae score
Basis:
animal #3
Time point:
other:
Score:
1
Remarks on result:
other:
Irritation parameter:
conjunctivae score
Basis:
mean
Time point:
other:
Score:
0.9
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #1
Time point:
other:
Score:
1.3
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #2
Time point:
other:
Score:
0
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
animal #3
Time point:
other:
Score:
0.3
Remarks on result:
other:
Irritation parameter:
chemosis score
Basis:
mean
Time point:
other:
Score:
0.6
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #1
Time point:
other:
Score:
1.3
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #2
Time point:
other:
Score:
0.3
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
animal #3
Time point:
other:
Score:
0
Remarks on result:
other:
Irritation parameter:
cornea opacity score
Basis:
mean
Time point:
other:
Score:
0.6
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #1
Time point:
other:
Score:
0.3
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #2
Time point:
other:
Score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
animal #3
Time point:
other:
Score:
0
Remarks on result:
other:
Irritation parameter:
iris score
Basis:
mean
Time point:
other:
Score:
0.1
Remarks on result:
other:

Applicant's summary and conclusion