Registration Dossier
Registration Dossier
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EC number: 464-510-9 | CAS number: -
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 464-510-9
- EC Name:
- -
- Cas Number:
- 147768-39-6
- Molecular formula:
- C10H23O3P
- IUPAC Name:
- 3-[(3-hydroxypropyl)(2-methylpropyl)phosphoryl]propan-1-ol
1
- Radiolabelling:
- yes
Results and discussion
- Transformation products:
- no
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 4
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 a-1
- DT50:
- > 1 yr
- pH:
- 7
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 a-1
- DT50:
- > 1 yr
- pH:
- 9
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 a-1
- DT50:
- > 1 yr
- Details on results:
- There was no evidence from the 31P NMR spectra to suggest that any sample degradation occurred during storage at 5°C for 5 days. Therefore, as less than 10% hydrolysis of the test material occurred after 5 days at 50°C, the half-life of the test item can be estimated to be greater than 1 year at 25 · C.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- the half-life of the test item can be estimated to be greater than 1 year at 25°C under the tested conditions (pH 4, 7 and 9).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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