D-Xylopyranose, oligomeric, 2-octyldodecyl xylosides

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: OECD guideline, GLP study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

yes

Remarks:

The deviations were considered not to have affected the quality or the interpretation of the results obtained.

GLP compliance:

yes (incl. QA statement)

Remarks:

2003-03-27

Type of method:

thermal analysis

Melting / freezing pt.:

ca. 25 °C

Atm. press.:

ca. 94.8 kPa

Remarks on result:

other: +/- 1.1 °C

Conclusions:

The mean solidification point of the test item was: 25.0°C ± 1.1°C.

Executive summary:

SOLIDIFICATION POINT

In compliance with Commission Directive 92/69/EEC - A1 method (1992) OECD Guideline No. 102 (1995)

Remark: the phase transition from the liquid state to the solid state of the test item is entitled “solidification point” instead of “freezing point” due to the temperature at which this transition occurred (25°C).

AMENDMENTS Amendment No. 1: a first assay on the Kofler hot bench was done, the melting point of the test item was lower than 50°C, the melting point test could not be performed due to the temperature range of the Kofler hot bench (from 50°C). Thus, a solidification point test (A01F) was performed.

The test item was melted in a water bath (at about 50°C), then the solidification point was done on the liquid test item to determine the solidification point.

DEVIATIONS The following deviations to the standard operating procedure were recorded: The test was performed directly in a cooling bath instead of a Dewar vessel. The precision of the thermometer (DEFITRACES No. PT02) was 0.1°C instead of 0.5°C. These deviations were considered not to have affected the quality or the interpretation of the results obtained.

RESULTS Solidification point (Assay No. 1): 26.1°C ± 0.1°C Solidification point (Assay No. 2): 24.5°C ± 0.1°C Solidification point (Assay No. 3): 24.3°C ± 0.1°C

CONCLUSION The mean solidification point of the test item was: 25.0°C ± 1.1°C.

Description of key information

In compliance with Commission Directive 92/69/EEC - A1 method (1992) OECD Guideline No. 102 (1995):

The test item was melted in a water bath (at about 50°C), then the solidification point was done on the liquid test item to determine the solidification point.

Remark: the phase transition from the liquid state to the solid state of the test item is entitled “solidification point” instead of “freezing point” due to the temperature at which this transition occurred (25°C)

The mean solidification point of the test item was: 25.0°C ± 1.1°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

25 °C