Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
explosive properties of explosives
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
05 May - 15 October 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.14 (Explosive properties)
Deviations:
no
GLP compliance:
yes
Key result
Parameter:
other: Explosive (not specified)
Remarks on result:
negative (not further specified)

The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion.

Using C10H12N2O5 as molecular formula and 240.2 g/mol as molecular weight, the oxygen balance for the test substance was calculated to be –140%. This is > –200% and therefore within the region where there may be a potential for explodability. However, there are no plosophores (bond groupings known to give explosive properties) or auxoploses (explosive enhancing groups) present in the structure. The relatively high oxygen balance is considered due to the presence of a keton group, hydroxyl groups and a cyclic ether five-ring in the molecular structure of the test substance. Overall consideration of the properties does not suggest a risk of explodability.

Interpretation of results:
GHS criteria not met
Conclusions:
The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion. The impurities, present for < 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

Anhydrothymidine is not explosive.

Description of key information

The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion. The impurities, present for < 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.

Anhydrothymidine is not explosive.

Key value for chemical safety assessment

Explosiveness:
non explosive

Additional information

Justification for classification or non-classification