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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-difluorobenzaldehyde
EC Number:
610-142-0
Cas Number:
437-81-0
Molecular formula:
C7 H4 F2 O
IUPAC Name:
2,6-difluorobenzaldehyde

Test organisms

Test organisms (species):
activated sludge of a predominantly domestic sewage
Details on inoculum:
activated sludge of the municipal treatment plant of D-31137 Hildesheim

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Test conditions

Nominal and measured concentrations:
Nominal 10 - 32 - 100 - 320 - 1000 [mg/L]
Reference substance (positive control):
yes

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
other: EC80
Effect conc.:
241 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
106 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Duration:
3 h
Dose descriptor:
other: EC20
Effect conc.:
46 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Results with reference substance (positive control):
Positive control substance: Copper-II-sulfate pentahydrate
EC50 = 105 mg/l
The EC50 value of the control substance is in the confidence range of 58-142 mg/l.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes