Registration Dossier
Registration Dossier
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EC number: 428-040-8 | CAS number: 138261-41-3
Endocrine disrupter mammalian screening – in vivo (level 3)
Administrative data
- Endpoint:
- endocrine disrupter mammalian screening – in vivo
- Type of information:
- other: EPA assessment report
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: reliable assessment by acknowledged authority (U.S. EPA)
Data source
Reference
- Reference Type:
- other: assessment report
- Title:
- EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals
- Author:
- Akerman, G. and Blankinship, A.
- Year:
- 2 015
- Bibliographic source:
- Endocrine Screening Program (EDSP) Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals, United States Environmental Protection Agency (EPA), Washington, USA
- Report date:
- 2015
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Based on weight of evidence considerations, there is no convincing evidence of potential interaction with the estrogen, androgen or thyroid pathways. Thus, the test substance is not considered to be an endocrine disruptor.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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