Registration Dossier

Diss Factsheets

Toxicological information

Endocrine disrupter mammalian screening – in vivo (level 3)

Administrative data

Endpoint:
endocrine disrupter mammalian screening – in vivo
Type of information:
other: EPA assessment report
Adequacy of study:
weight of evidence
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: reliable assessment by acknowledged authority (U.S. EPA)

Data source

Reference
Reference Type:
other: assessment report
Title:
EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals
Author:
Akerman, G. and Blankinship, A.
Year:
2015
Bibliographic source:
Endocrine Screening Program (EDSP) Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals, United States Environmental Protection Agency (EPA), Washington, USA
Report date:
2015

Materials and methods

Results and discussion

Applicant's summary and conclusion

Conclusions:
Based on weight of evidence considerations, there is no convincing evidence of potential interaction with the estrogen, androgen or thyroid pathways. Thus, the test substance is not considered to be an endocrine disruptor.