Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Endocrine disrupter mammalian screening – in vivo (level 3)

Administrative data

endocrine disrupter mammalian screening – in vivo
Type of information:
other: EPA assessment report
Adequacy of study:
weight of evidence
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: reliable assessment by acknowledged authority (U.S. EPA)

Data source

Reference Type:
other: assessment report
EDSP Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals
Akerman, G. and Blankinship, A.
Bibliographic source:
Endocrine Screening Program (EDSP) Weight of Evidence Conclusions on the Tier 1 Screening Assays for the List 1 Chemicals, United States Environmental Protection Agency (EPA), Washington, USA
Report date:

Materials and methods

Results and discussion

Applicant's summary and conclusion

Based on weight of evidence considerations, there is no convincing evidence of potential interaction with the estrogen, androgen or thyroid pathways. Thus, the test substance is not considered to be an endocrine disruptor.