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EC number: -
CAS number: -
an acute oral toxicity study (limit test) performed according to OECD
Guideline 423 and in compliance with GLP, 6 female Sprague Dawley rats
were given a single oral (gavage) dose of test item at 2000 mg/kg bw.
Animals were then observed for mortality, clinical signs and bodyweights
for 14 days and were all sacrificed for macroscopic examination.
mortality occurred during the study. No clinical signs related to the
administration of the test item were observed. The body weight evolution
of the animals remained normal throughout the study. The macroscopical
examination of the animals at the end of the study did not reveal
the test conditions, the oral LD50 of test item is higher than 2000
mg/kg bw in female rats therefore it must not be classified according to
the CLP Regulation (EC) No. 1272/2008 and Globally Harmonized System
study is considered as acceptable and satisfies the requirement for
acute oral toxicity endpoint.
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