Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 July to 25 August 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to an internationally recognised method, and under GLP, but accuracy is limited by measuring range and extrapolation. The substance is adequately identified, but the composition is incomplete. Therefore validation applies with restrictions.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23. Mar. 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
Regulation (EC) N°440/2008, as modified by Reg.(EC) No 761/2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
issued on 12/01/2007
Type of method:
effusion method: Knudsen cell
Specific details on test material used for the study:
Storage condition of test material: The test item was stored in a closed vessel at room temperature (20 +/-5°C).
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0.138 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
0.223 Pa

Table 4.6/1: Vapour Pressures (Effusion Method)

 

Experiment No.

T (°C)

T (K)

P (Pa)

Stand. Dev. P (Pa)

RSD P (%)

1

30

303.2

0.356

0.111

31.2

2

45

318.2

1.32

0.197

15.0

  

Vapour pressure at two different temperatures was examined. For these temperatures, 1/T was plotted against log (P):

log (VP) = -3649.4 x (1/T) + 11.59

The linear regression gave a correlation coefficient r of - 1, as only two experiments could be performed for the test item.

For the test item, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:

Vapour pressure at 20 °C: 0.138 Pa

Vapour pressure at 25 °C: 0.223 Pa

Conclusions:
Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).
Executive summary:

The vapour pressure of test item was measured under GLP according to OECD 104 / EU A4 guideline, effusion method with Knudsen cell (weight loss).

Determinations were conducted at 30 and 45°C, with triplicate measurements for each of the four cells.

The vapour pressure at 25°C of the test item was extrapolated from the regression as 0.223 Pa.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:
0.223 Pa
at the temperature of:
25 °C

Additional information

A reliable experimental study, conducted according to a recognized EC method and under GLP, is available.

Despite restrictions due to technical inaccuracy and incomplete test item identification, it is considered as key study, and the result is retained as key data.