Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 954-921-6
CAS number: -
Table 1: Acute oral toxicity of the test
substance in rats, application scheme and mortality data
Dose [mg/kg body weight]
Volume Dosed [mL]
An acute oral toxicity study (OECD 425, GLP
compliant) (up and down procedure) was conducted with 4 female Crl:WI
rats. Animals were treated with a single oral (gavage) dose of the test
substance, at a dose level of 1750 or 5000 mg/kg body weight (bw)
followed by a 14 day observation period. The animals were fasted
overnight prior to treatment and food was returned 3 hours after dosing.
Animals were observed individually after dosing at 30 minutes, then at
1, 2, 3, 4 and 6 hours post treatment and once each day for 14 days,
thereafter. Body weight was measured on Day -1, just before dosing and
weekly thereafter. All animals were examined macroscopically at the end
of the observation period. There was no mortality during the study. No
clinical signs were observed during the observation period. There were
no treatment related effects on body weight or body weight gain. Body
weights were within the range commonly recorded for this strain and age.
At necropsy, there were no observations to be reported at a dose level
of 1750 and 5000 mg/kg bw.
Under the conditions of this study, the
acute oral median lethal dose (LD50) of the test substance, the test
substance, was greater than 5000 mg/kg bw in female Crl:WI rats.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again