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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06 Dec 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
Version / remarks:
July 2013
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
Cas Number:
2061933-85-3
Molecular formula:
C23H19Cl2F4N3O4
IUPAC Name:
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
Test material form:
solid: particulate/powder

Reagents

Reagent:
water

Results and discussion

pH value
Key result
pH value:
6.81
Temp.:
20 °C
Concentration:
1 vol%

Any other information on results incl. tables

RESULTS:

The test substance formed a dispersion in water at a loading rate of 1 % w/v. The pH values of the 1 % w/v aqueous dispersions are shown below.

- Mean pH value: 6.81

- Temperature: 20 °C

- pH of the high purity water: 6.85

Table 1: pH value determination

 

Determination

pH Value

 

Overall Mean pH

After 1 Minute

After 2 Minutes

After 10 Minutes

1

7.78

7.62

6.82

 

6.81

2

7.74

7.37

6.80

Applicant's summary and conclusion

Conclusions:
The pH of the test substance, as a 1 % w/v aqueous dispersion, is 6.81 at 20 °C.
Executive summary:

The pH of the test substance was ssessed in accordance with OECD 122 and in compliance with GLP. The pH value, as a 1 % w/v aqueous dispersion, has been determined to be 6.81 at 20 ºC. This value was the mean of duplicate sample preparations, with individual replicate pH values of 6.80 and 6.82 being obtained.