Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

All enzyme classes are readily biodegradable. Degradation products are primarily peptides and amino acids, then carbon dioxide and water which cause no harm to nature [1]. OECD ready biodegradability tests have been conducted on lipases, cellulases and amylase with results (92 to 99% DOC removal) that surpass the OECD threshold limit of 70% DOC removal [2].


[1] Enzymes REACH Consortium (2010). Data waiving argumentation for technical enzymes.

[2] Bergman,A. and Broadmeadow,A. (1997) An overview of the safety evaluation of the Thermomyces lanuginosus xylanase enzyme (SP 628) and the Aspergillus aculeatus xylanase enzyme (SP 578). Food additives and contaminants 14, 389-398

Additional information