Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 239-360-0 | CAS number: 15323-35-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- Physical Appearance (with color): Off-white crystal
Storage Condition: Ambient (21 to 29°C) - Key result
- Water solubility:
- 4.84 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- - System suitability: System suitability meets the acceptance criterion as the % RSD obtained was 0.12% to 1.15% which is less than 2.0% and theoretical plates obtained was 6626 to 10415 which is more than 2000 and asymmetry obtained was 1.03 to 1.19 which is less than 2.0.
- Specificity: Specificity meets the acceptance criterion for the test item as the interference obtained for diluent was 1.57% and diluent fortified with water was 4.30% which is < 30 % of the standard response at LOQ.
- Limit of Detection (LOD) and Limit of Quantification (LOQ): The LOD was determined at 0.10 mg/L concentration based on S/N ≈ 2/1 and LOQ was determined at 0.49 mg/L concentration based on S/N ≥ 10/1 for the test item.
- Linearity: Linearity meets the acceptance criterion for Phantolid Crystals as the correlation coefficient obtained was 0.9992 to 1.0000 which is ≥ 0.99.
- Accuracy (% Recovery) and Precision (% RSD): Recovery for Phantolid Crystals meets the acceptance criterion as the % recovery obtained was 94.42% for LOQ and 101.52% for 10 LOQ which is within the range 70 % to 110 % of the nominal concentration for each fortification level. Precision meets the acceptance criterion as the % RSD for Phantolid Crystals obtained was 0.93% for LOQ and 0.53% for 10 LOQ which is ≤ 20.0%.
Reference
Description of key information
The water solubility of the test substance is 4.84 mg/L (OECD 105 and GLP).
Key value for chemical safety assessment
- Water solubility:
- 4.84 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
