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EC number: 600-386-6 | CAS number: 10305-38-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h) > 100 mg/L for Pseudokirchnerella subcapitata (OECD 201)
Key value for chemical safety assessment
Additional information
One study is available on the toxicity of 3-(Hexyloxy)-1.2-propanediol (CAS No. 10305 -38 -1) to algae. This key study was performed according to OECD guideline 201 and GLP (Bouwman, 2013). The test organism Pseudokirchnerella subcapitata was exposed to the test substance in a static system for 72 hours, at nominal test concentrations of 0, 0.10, 1, 10 and 100 mg/L Analyses of the samples taken during the study were based on total organic carbon, since it proved impossible to develop a specific analytical method to accurately measure 3-(Hexyloxy)-1.2-propanediol concentrations in aquatic samples. Results showed measured carbon concentrations of 62.5, 63.3 and 61.0 mg/l in samples taken from nominally 100 mg/l at the start, after 24 and 72 hours of exposure, respectively. These results showed that the measured concentration was stable and, based on a carbon content of 61%, actual concentrations were between 100 and 104% relative to nominal. Given these results, the effect parameters were based on nominal concentrations. No significant inhibition of growth rate and yield was observed at 100 mg/L, and hence, NOEC and EC50 values were reported as ≥ 100 mg/L and > 100 mg/L, respectively.
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