3-ethoxy-4,6-difluoro-7-hexyloxy-dibenzothiophene

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

27.02.2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Qualifier:

according to guideline

Guideline:

ISO 13320 (Particle size analysis - Laser diffraction methods)

GLP compliance:

no

Type of method:

Laser scattering/diffraction

Type of particle tested:

agglomerate

Type of distribution:

volumetric distribution

Key result

Percentile:

D10

Mean:

ca. 2.6 µm

Remarks on result:

other: St. dev. not determined

Key result

Percentile:

D50

Mean:

ca. 13 µm

Remarks on result:

other: st. dev. not determined.

Key result

Percentile:

D90

Mean:

ca. 61.3 µm

Remarks on result:

other: st. dev. not determined.

The test item consisted of transparent crystalline particles which appeared flake-shaped.

The particles were introduced to the analyser beam by the dry powder feeder by direct spraying

through the measurement area. The powder was loosened by an integrated vibrator. The particles

were dispersed and fed to the optical system by pressurized dry air (1.5 bar). After passing the

analyser beam the sample was collected in a vacuum cleaner.

After adjusting the laser, measuring the background (demineralized water with 1 % detergent) and adjusting the correct particle concentration (obscuration) the measurement was started. The control software automatically performed three measurements. The average of these three measurements was given as result. Two test series of three measurements each were performed. The measurement time was 8 s.

For each test series fractions (left axis of the ordinate) and the siftings (right axis of the ordinate) are presented in percent by volume as a function of the particle size. Median values were calculated from unrounded values.

 

The median particle size L50(D (v, 0.5): 50 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L50= 12.74 μm

2ndtest series: L50= 13.25 μm

The average of the median particle size L50was: L50= 13.0 μm

 

The particle size L10 (D (v, 0.1 ): 10 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L10=2.61μm

2ndtest series: L10=2.66μm

The average of the particle size L10was: L10= 2.6 μm

 

The particle size L90(D (v, 0.9): 90 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L90=57.91μm

2ndtest series: L90=64.59μm

The average of the particle size L90was: L90= 61.3μm

 

The maximum was observed at approximately 10µm. Additionally a shoulder were observed at

 and approximately 250µm.

Conclusions:

The median particle size L50 of the test item deduced from the particle size distributions was 13.0 μm.

Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 13.0 μm.

Description of key information

The median particle size L50 of the test item deduced from the particle size distributions was 13.0 µm.