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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26 April 1996 to 29 April 1996
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
Deviations:
no
GLP compliance:
yes
Type of method:
cascade impaction
Remarks:
multistage impactor and sieving
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Name: FAT 40'549/A
Description: yellow brown powder
Batch: TV-1
Stability: stable at room temperature
Expiry date: 01 January 2001
Percentile:
D50
Mean:
ca. 66 µm
Remarks on result:
other: L50 = 66 μm
No.:
#1
Size:
>= 0.36 - < 0.75 µm
Distribution:
0.12 %
No.:
#2
Size:
>= 0.75 - < 1.54 µm
Distribution:
0.27 %
No.:
#3
Size:
>= 1.54 - < 3.07 µm
Distribution:
0.52 %
No.:
#4
Size:
>= 3.07 - < 6.14 µm
Distribution:
1.2 %
No.:
#5
Size:
>= 6.14 - < 11.93 µm
Distribution:
3.79 %
No.:
#6
Size:
>= 11.93 - < 24.46 µm
Distribution:
8.92 %
No.:
#7
Size:
>= 24.46 - < 63 µm
Distribution:
30.22 %
No.:
#8
Size:
>= 63 - < 100 µm
Distribution:
35.46 %
No.:
#9
Size:
>= 100 - < 200 µm
Distribution:
18.96 %
No.:
#10
Size:
>= 200 µm
Distribution:
0.51 %
Conclusions:
The Mass median diameter of FAT 40549 was found to be 66 μm.
Executive summary:

The purpose of the study is to determine the particle size distribution of FAT 40'549/A according to the OECD guideline 110.

The determination of the particle size distribution using the applied methods was limited to the range 0.36 μm - < 63 μm (multistage impactor) 63 μm - < 100 μm, 100 μm - < 200 μm and > 200 μm (sieving).

The substance FAT 40'549/A is a powder with a rate of 0.51 mass-% greater than 200 μm. The particle size distribution further has been determined to be 4.4 % < 10 μm. 50 mass-% of the substance were smaller than 66 μm (MMD). The maximum of mass frequency was a about 45 μm.

Description of key information

The Mass median diameter of FAT 40549 was found to be 66 μm

Additional information

The purpose of the study is to determine the particle size distribution of FAT 40'549/A according to the OECD guideline 110.

The determination of the particle size distribution using the applied methods was limited to the range 0.36 μm - < 63 μm (multistage impactor) 63 μm - < 100 μm, 100 μm - < 200 μm and > 200 μm (sieving).

The substance FAT 40'549/A is a powder with a rate of 0.51 mass-% greater than 200 μm. The particle size distribution further has been determined to be 4.4 % < 10 μm. 50 mass-% of the substance were smaller than 66 μm (MMD). The maximum of mass frequency was a about 45 μm.