Hydrocarbons, C11-C16, n-alkanes, isoalkanes,

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Study period:

Experimental Starting Date: 03 December 2013 Experimental Completion Date: 10 March 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Justification for type of information:

The hypothesis for the analogue approach is that the test substance, Hydrocarbons, C10-C13, n-alkanes, isoalkanes, <2% aromatics contains constituents which are also constituents of the target substance, Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics. The substances have overlapping constituents and therefore have qualitatively similar properties (RAAF Scenario 2 applies).

Reason / purpose for cross-reference:

read-across: supporting information

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

199 - 219 °C

Atm. press.:

101.8 kPa

Decomposition:

no

Key result

Boiling pt.:

472 - 492 K

Atm. press.:

101.8 kPa

Decomposition:

no

Results

The thermographic data for determinations 1 and 2 are shown in the tables below and the thermograms are shown in Attachment 1 of this summary.

Table 1: Thermographic Data – Determination 1

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	198.77	472	218.31	491

 

 Atmospheric pressure: 101.8kPa

Table 2: Thermographic Data – Determination 2

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	199.58	473	218.8	492

 

Atmospheric pressure: 101.8 kPa

 

Overall boiling temperature: 199 - 219°C (472 – 492 K)at 101.8 kPa

 

Conclusions:

The boiling temperature range of the test item has been determined to be 199 -219°C (472 - 492 K) at 101.8 kPa using a relevant test method. The result is considered reliable.

Executive summary:

The determination was carried out by differential scanning calorimetry (DSC) using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation(EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Conclusion

The boiling temperature range of the test item has been determined to be 199 - 219°C (472 - 492 K) at 101.8 kPa

Reference 2

Endpoint:

boiling point

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Study period:

Experimental Starting Date: 03 December 2013 Experimental Completion Date: 11 March 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Justification for type of information:

The hypothesis for the analogue approach is that the test substance, Hydrocarbons, C12-C15, n-alkanes, isoalkanes <2% aromatics contains constituents which are also constituents of the target substance, Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics. The substances have overlapping constituents and therefore have qualitatively similar properties (RAAF Scenario 2 applies).

Reason / purpose for cross-reference:

read-across: supporting information

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

229 - 248 °C

Atm. press.:

101.8 kPa

Decomposition:

no

Key result

Boiling pt.:

503 - 521 K

Atm. press.:

101.8 kPa

Decomposition:

no

Results

The thermographic data for determinations 1 and 2 are shown in the tables below and the thermograms are shown in Attachment 1 of this summary.

Table 1: Thermographic Data – Determination 1

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	229.87	503	249.14	522

 

 Atmospheric pressure: 101.8kPa

 

Table 2: Thermographic Data – Determination 2

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	228.89	502	247.24	520

 

Atmospheric pressure: 101.8 kPa

 

Overall boiling temperature: 229 - 248°C (503 – 521 K)at 101.8 kPa

Conclusions:

The boiling temperature range of the test item has been determined to be 229 -248°C (503 - 521 K) at 101.8 kPa using a relevant test method. The result is considered reliable.

Executive summary:

The determination was carried out by differential scanning calorimetry (DSC) using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation(EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Conclusion

The boiling temperature range of the test item has been determined to be 229 - 248°C (503 - 521 K) at 101.8 kPa

Reference 3

Endpoint:

boiling point

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Study period:

Experimental Starting Date: 04 December 2013 Experimental Completion Date: 11 March 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The hypothesis for the analogue approach is that the test substance, Hydrocarbons, C14-C16, n-alkanes, isoalkanes, <2% aromatics contains constituents which are also constituents of the target substance, Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics. The substances have overlapping constituents and therefore have qualitatively similar properties (RAAF Scenario 2 applies).

Reason / purpose for cross-reference:

read-across: supporting information

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

>= 258 - <= 273 °C

Atm. press.:

101.8 kPa

Decomposition:

no

Key result

Boiling pt.:

>= 531 - <= 547 K

Atm. press.:

101.8 kPa

Decomposition:

no

Results

The thermographic data for determinations 1 and 2 are shown in the tables below and the thermograms are shown in Attachment 1 of this summary.

Table 1: Thermographic Data – Determination 1

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	258.64	532	274.44	548

 

 Atmospheric pressure: 101.8kPa

 

Table 2: Thermographic Data – Determination 2

Thermal event	Interpretation	Onset temperature		Endset temperature
		°C	K	°C	K
Endotherm	Boiling temperature	257.93	531	272.36	546

 

Atmospheric pressure: 101.8 kPa

 

Overall boiling temperature: 258 - 273°C (531 – 547 K)at 101.8 kPa

 

Conclusions:

The boiling temperature range of the test item was determined to be 258 - 273°C (531 - 547 K) at 101.8 kPa using relevant test method. The result is considered reliable.

Executive summary:

The determination was carried out by differential scanning calorimetry (DSC) using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation(EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Conclusion

The boiling temperature range of the test item has been determined to be 258 - 273°C (531 - 547 K) at 101.8 kPa.

Description of key information

Only supporting data is available for Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics. However, data is available for structural analogues, Hydrocarbons, C10-C13, n-alkanes, isoalkanes, <2% aromatics; Hydrocarbons, C12-C15, n-alkanes, isoalkanes, <2% aromatics; and Hydrocarbons, C14-C16, n-alkanes, isoalkanes, <2% aromatics and presented in the dossier. The hypothesis for the analogue approach is that the test substances, Hydrocarbons, C10-C13, n-alkanes, isoalkanes, <2% aromatics; Hydrocarbons, C12-C15, n-alkanes, isoalkanes <2% aromatics; and Hydrocarbons, C14-C16, n-alkanes, isoalkanes, <2% aromatics contain constituents which are also constituents of the target substance, Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics. The substances have overlapping constituents and therefore have qualitatively similar properties (RAAF Scenario 2 applies).

The boiling range of Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics was determined to be 212.1 -258.2°C at 101.8 kPa.

Additional information

There are no reliable measured boiling point data for the registration substance. However, reliable data are available for related substances in the relevant carbon number range, including other Fischer-Tropsch process-derived substances.

Hydrocarbons, C11-C16, n-alkanes, isoalkanes, <2% aromatics has a measured boiling range of 212.1 -258.2°C at 1013 hPa using the distillation method. Full study details are not available therefore reliability could not be assigned to these data.

Reliable data are, however, available for related substances in the relevant carbon number range, including other Fischer-Tropsch process-derived substances.

In OECD 103 studies using Differential Scanning Calorimetry (DSC), which were conducted in compliance with GLP, Hydrocarbons, C10-C13, n-alkanes, isoalkanes, <2% aromatics (GTL Solvent GS190), Hydrocarbons, C12-C15, n-alkanes, isoalkanes, <2% aromatics (GS215) and Hydrocarbons, C14-C16, n-alkanes, isoalkanes, <2% aromatics (GS250) had measured boiling ranges of 199 - 219°C (472 - 492 K), 229 - 248°C (503 - 521K) and 258 - 273°C (531 - 547K) at 101.8 kPa, respectively.

The results are considered to be reliable and are used as weight of evidence.