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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2000.04.04-2000.09.21
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study performed in accordance with test guideline
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
GLP compliance:
yes
Type of method:
flask method
Water solubility:
> 4 000 g/L
Temp.:
20 °C
pH:
9.1
Details on results:
NA

NA

Conclusions:
The solubility of L-TEE in water was determined in accordance to EC Method A6 and OECD Guideline 105.
The solubility of L-TEE in double-distilled water was determined to be greater than 4000 g/L with a nominal pH of 9.1.
Executive summary:

The solubility of L-TEE in water was determined in accordance to EC Method A6 and OECD Guideline 105.

To 5 mL double-distilled water, an amount of 10 g of L-TEE was added twice. As it fully dissolved the test was stopped. Cooling the solution to 20°, no deposit was observed.

The solubility in double-distilled water was determined by a simplified (non-analytical) shake flask procedure to be > 4000 g/L with a resultant pH of nominally 9.1.


Description of key information

The water solubility of L-TEE was determined to be >4000 g/L at 20°C.

Key value for chemical safety assessment

Water solubility:
4 000 g/L
at the temperature of:
20 °C

Additional information

The solubility of L-TEE in water was determined in accordance with EC Method A6 and OECD Guideline 105.

To 5 mL double-distilled water, an amount of 10 g of L-TEE was added twice. As it fully dissolved, the test was stopped. Cooling the solution to 20°, no deposit was observed. Therefore the solubility of the test substance at this latter temperature is considered to be in excess of 4000 g/L.

The solubility in double-distilled water was determined by a simplified (non-analytical) shake flask procedure to be > 4000 g/L with a resultant pH of nominally 9.1.