Registration Dossier

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Administrative data

Key value for chemical safety assessment

Additional information

Short description of key information:
Isosorbide mononitrate did not produce gene mutations or chromosome aberrations. The read-across approach is applied in order to transfer the isosorbide mononitrate information to isosorbide dinitrate.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

According to Directive 67/548/EEC and to Regulation (EC) n. 1272/2008, the substance should not be classified for mutagenicity.