Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Aquatic toxicity testing in daphnids and freshwater algae led to the following acute toxicity values:

  • 48 -hour EC50 in daphnids = 684 µg/L
  • 72 -hour ErC50 in freshwater algae = 1651 µg/L

Additional information

Studies on the acute aquatic toxicity of (R)-3-Amino-2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol L-tartrate are available for two trophic levels. Both studies were conducted according to OECD guidelines and GLP. The most sensitive species was Daphnia magna with an 48 -hour EC50 of 684 µg/L.