Registration Dossier
Registration Dossier
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EC number: 418-240-3 | CAS number: 74401-04-0 N-METHYL-4-(P-FORMYLSTYRYL)-PYRIDINIUM METHYLSULFATE; SBQ; SBQ-SALZ
Endpoint summary
Administrative data
Description of key information
Additional information
Adequate chronic toxicity data are not available for the substance, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available.
Despite the substance has a log Kow lower than 4 (indicating a low potential for bioaccumulation), it is not readily (bio)degradable.
According to the CLP Regulation (EC 1272/2008), acute aquatic toxicity is normally determined using a fish 96-hour LC50 , a crustacean species 48-hour EC50 and/or an algal species 72- or 96-hour EC50.
Fish
The potential of the test substance to induce short-term toxicity to fish was investigated on Oncorhynchus mykiss in accordance with the EU method C.1. The fish were exposed to the test substance at the limit concentration of 100 mg/l for a period of 96 hours, under static conditions. During the test, the measured concentrations were 91 - 107% of the nominal value.
LC50 (96h) > 100 mg/L (nominal)
Invertebrates
The potential of the test substance to induce short-term toxicity to aquatic invertebrates was investigated on Daphnia magna in accordance with the EU method C.2 (92/69/EEC).
During the test, the measured concentrations were 85 - 109% of the nominal values. The EC50 at 48h was found to be equal to 11 mg/L.
Aquatic algae
The potential of the test substance to induce toxicity to aquatic algae and cyanobacteria was investigated on Desmodesmus subspicatus in accordance with the EU method C.3 (92/69/EEC). 84 % of the initial concentration was loss during the test. The loss of the test substance may be attributed to the light sensitive nature of the substance and/or incorporation into the algal biomass.
EC50 (72 h) > 16 mg/L and NOEC (72h) = 16 mg/L both for the biomass and the growth rate.
In conclusion, the substance is classified in Aquatic Chronic 3 (H412) according to the classification criteria of the CLP Regulation n. 1272/2008.
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