Registration Dossier
Registration Dossier
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EC number: 454-720-9 | CAS number: 161596-47-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 96/54/EG, B.1tris (Akute-toxische-Klassen-Methode); OECD 423
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- no
Test animals
- Species:
- other: rat, Wistar Hsd Cpb:WU
Administration / exposure
- Vehicle:
- other: Trinkwasser mit 2 % Cremophor EL "ENGLISH" Drinking water with 2 % cremophor EL
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Female: 2000 mg/kg bw; Number of animals: 3; Number of deaths: 0
- Clinical signs:
- other: Signs of toxicity related to dose levels: Bei 2000 mg/KG wurden folgende klinische Symptome beobachtet: abnehmender Bewegungsdrang, unkoordinierte Bewegungen, verengte Lidspalten bzw. geschlossene Augenlider, erschwerte Atmung, gesträubtes Fell. (Z
- Gross pathology:
- Effects on organs:
Bei den nach Ende der Studie getöteten Tieren wurden keine
auffälligen pathologischen Befunde beobachtet.
"ENGLISH"
No conspicuous pathological findings were observed in the
animals killed at the end of the study.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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