Registration Dossier
Registration Dossier
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EC number: 806-451-7 | CAS number: 42532-60-5
Endpoint summary
Administrative data
Description of key information
Additional information
C4 fluorinated isonitrile is fully fluorinated at all atoms except the nitrile group. It is a gas under normal conditions, with a boiling point of -4.7 °C. It is used as an inert insulating gas for high-voltage electrical components. Potential releases would be during transfer, filling, or emptying steps, or during catastrophic failure of the filled component. Such releases would be to the atmospheric compartment only. In the atmosphere, this substance is subject to reaction with hydroxyl radical with an atmospheric lifetime of ca. 30 years. This substance does not attain high concentrations in water, and is hydrolytically unstable. When a headspace containing this substance is held in contact with water in closed systems, substantial portions dissolve in the water phase and form heptafluoroisobutyramide. However as a gas, limited contact with the aquatic compartment is expected. Hydrolysis in the atmosphere cannot be excluded given the facile reaction with water in closed systems and the relatively long atmospheric lifetime. The effect of hydrolysis in the atmosphere would be to reduce atmospheric lifetime of the isonitrile, with deposition of the amide to the terrestrial and the aquatic compartments. The Global Warming Potential (100-y integrated time horizon) relative to carbon dioxide is 2100.
Most degradation is expected to occur in the atmosphere. As a gas with a measured Henry's Law constant of 590 atm∙m³/mole (log HLC = 4.4), the C4 fluorinated isonitrile is not expected to partition to aquatic or terrestrial compartments. Therefore, biodegradation is not relevant. In closed bottle biodegradation experiments, the parent hydrolyzed to form the amide, but the amide was not subject to biodegradation. The amide has a water solubility of 17,800 mg/L. Amide which may form or be deposited in surface waters is not expected to bioaccumulate based on a measured log Kow of 1.7. The protein binding mechanisms often cited for longer perfluorinated acids such as PFOS and PFOA are not relevant to this compound owing to its lack of a negatively charged head group and short length. If the amide forms on reaction of gas-phase isonitrile with pore water, the resulting material is expected to be mobile in soil based on a Koc of 42.4.
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