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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 2020-02-26 to 2020-05-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
440/2008/EC, 30 May 2008
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
dynamic method
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
5 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
8 Pa
Key result
Vapour pressure:
54 Pa

The vapour pressure was measured in the temperature range of 115.6 to 135.5 °C. The measured vapour pressure values together with the measured temperatures are listed in the following table.

Results of the dynamic method

No.

Temperature / °C

Vapour pressure / hPa

Remark

1

115.6

29.2

measured up

2

123.8

37.5

measured up

3

125.9

44.6

measured up

4

128.5

52.1

measured up

5

131.5

59.5

measured up

6

134.2

67.8

measured up

7

135.5

72.5

measured up

8

135.3

69.8

measured down

9

132.6

61.5

measured down

10

127.5

47.3

measured down

 

The logarithm of the vapour pressure was plotted as a function if the inverse temperature 1/T. From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation (log p = A + B/T) can be derived by regression of the data points toA = 11.8405 and B = -3266.10. Tha vapour pressure of the test item at 20, 25 and 50 °C was calculated by extrapolation.

 

Temperature / °C

Vapour pressure / hPa

20

0.05

25

0.08

50

0.54

Conclusions:
The estimated vapour pressure of the test item at 20 °C is 5 Pa.
Executive summary:

The vapour pressure of the test item was determined according to Regulation (EC) No. 440/2008 Method A.4. Vapour pressure and OECD Test Guideline 104 (2006). The dynamic method was used to determine the vapour pressure in the temperature range of 115.6 to 135.5. 10 measurement points were recorded.The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C to be 5, 8 and 54 Pa, respectively.

Description of key information

The estimated vapour pressure of the test item at 20 °C is 5 Pa.

Key value for chemical safety assessment

Vapour pressure:
5 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the test item was determined according to Regulation (EC) No. 440/2008 Method A.4. Vapour pressure and OECD Test Guideline 104 (2006). The dynamic method was used to determine the vapour pressure in the temperature range of 115.6 to 135.5. 10 measurement points were recorded.The vapour pressure of the test item was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °Cto be 5, 8 and 054 Pa, respectively.