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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The EC50 value was determined as 69.87 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
69.87 mg/L

Additional information

An activated sludge test has been conducted on tetrahydromethylphthalic anhydride (MTHPA), of which 3 -MTHPA D4 is an isomer following OECD test methds. An EC50 value of 69.87 mg/L was determined. An accurate NOEC value could not be determined, being lower than the lowest concentration of 10 mg/L investigated. Respiration rates were influenced (inhibited) dose dependently over the whole concentration range.