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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
8.11.2020 - 26.2.2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: Knudsen cell
Key result
Test no.:
#1
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0 Pa
Key result
Test no.:
#2
Temp.:
ca. 25 °C
Vapour pressure:
ca. 0 Pa

The mass of sample weighed for each assay was reported in the table below. The sample was placed in a Knudsen effusion cell. Then the cell was placed in the apparatus.

 

Assay No.

Test temperature t (°C)

Mass of test item (mg)

Knudsen effusion cell aperture size (µm)

Log P

(Pa)

2

85

6.50

279.9

-0.784

3

70

8.45

279.9

-1.569

5

60

8.45

279.9

-2.178

6

55

8.45

279.9

-2.521

 

 No degradation of the test item was observed.

Conclusions:
2-Amino-5-chloro-N,3-dimethylbenzamide is a solid at 20°C with a capour pressure of 1.0855 10^-5 Pa.
Executive summary:

By dynamic effusion method with a micro-balance vapour pressure for 2 -amino-5-chloro-N,3-dimethylbenzamide was evaluated according to OECD guideline 104 (2006) and EC A.4 (2009).

The vapour pressure (P) of the test item extrapolated is 1.0855 x 10-5 Pa at 20 °C and calculated at 2.6515 x 10-5 Pa at 25 °C.

The volatility (H) of the test item calculated at 20 °C is 7.7846 x 10-6 Pa.m3.mol-1.

Description of key information

The vapour pressure (P) of 2 -amino-5 -chloro-N,3 -dimethylbenzamide is 1.0855 x 10-5 Pa at 20 °C and calculated at 2.6515 x 10-5 Pa at 25 °C.

The volatility (H) of 2 -amino-5 -chloro-N,3 -dimethylbenzamidec alculated at 20 °C is 7.7846 x 10-6 Pa.m3.mol-1.

Key value for chemical safety assessment

Additional information