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Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental starting date: 20 March 2018. Experimental completion date: 24 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Results and discussion

Vapour pressure
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

Results:

Recorded temperatures, mass differences and the resulting calculated vapor pressure are shown for runs 1 - 10 in attached background material.

Graphs of Log10 VP vs Reciprocal Temperature are also included in background material.

Statistical data using an unweighted least squares method and the common logarithm of the vapor pressure at 25 °C (298 K) generated from the graphs of nine runs are shown in the following table:

Run

Slope

Standard Error of Slope

Intercept

Standard Error of Intercept

Log10Vp at 25°C

2

-3942

469

8.793

1.121

-4.427385

3

-4477

524

9.916

1.254

-5.098859

4

-5032

476

11.156

1.139

-5.720109

5

-4812

920

10.566

2.199

-5.572864

6

-4500

674

9.801

1.612

-5.293632

7

-4516

829

9.815

1.982

-5.330610

8

-5355

561

11.789

1.342

-6.172977

9

-4542

435

9.797

1.040

-5.436182

10

-5432

1146

11.86

2.740

-6.361644

Mean Log10 Vp at 25°C: -5.49

Vapour pressure at 25°C: 3.23 x 10-6 Pa

Applicant's summary and conclusion

Conclusions:
The vapor pressure of the test item has been determined to be 3.2 x 10-6 Pa at 25 ºC.
Executive summary:

The vapor pressure of CIM-43 has been determined to be 3.2 x 10-6 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008, and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.