Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 949-859-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
According to conditions described in Column 2 of Section 8.5.2 of Annex VIII testing by the inhalation route is appropriate if exposure of humans via inhalation is likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size.
As the substance has a low vapor pressure (6.1 x 10-7 Pa at 25°C), therfore exposure by inhalation of vapor is unlikely to occur. Furthermore the substance is only used as a liquid substance (as such or in a formulation (of lubricant additives, lubricants and greases)). Based on its use the possibility of exposure of workers to aerosols, particles or droplets of an inhalable size can be excluded. Since the criteria in Column 2 of Section 8.5.2 are not fulfilled testing by the inhalation route for the substance is considered not appropriate and thus testing is waived.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 19 Jun 2019 - 02 Aug 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: isothermal thermogravimetry
- Specific details on test material used for the study:
- Decomposition: 200°C
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of the substance at 20°C and 25°C was determined to be 2.5E-7 Pa and 6.1E-7 Pa, respectively.
- Executive summary:
The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study based on EC A.4, OECD 104 and OPPTS 830.7950. Validation of the method was performed using a set of five reference substances.
The vapour pressure regression curve (log PT as function of 1/T; with T in K) of the substance was constructed from weight losses measured at 150°C, 160°C, 170°C and 180°C.
The vapour pressure of the substance at 20°C and 25°C was calculated from the vapour pressure curve to be 2.5E-7 Pa and 6.1E-7 Pa, resp.
Table: Results of the vapour pressure isothermal TGA analysis (substance)
Temperature |
Weight loss |
νT |
log νT |
log PT |
PT |
150 |
1.69063 |
2.02 x 10-4 |
-3.70 |
0.38 |
2.4 |
|
1.61590 |
1.93 x 10-4 |
-3.71 |
0.36 |
2.3 |
160 |
3.05539 |
3.65 x 10-4 |
-3.44 |
0.71 |
5.1 |
|
3.02549 |
3.61 x 10-4 |
-3.44 |
0.70 |
5.0 |
170 |
6.23354 |
7.44 x 10-4 |
-3.13 |
1.10 |
13 |
|
5.80625 |
6.93 x 10-4 |
-3.16 |
1.06 |
11 |
180 |
11.2987 |
1.35 x 10-3 |
-2.87 |
1.43 |
27 |
|
10.2183 |
1.22 x 10-3 |
-2.91 |
1.37 |
23 |
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Manufacture name:
- Manufacture of the substance
- Name of activity / technique:
- Manufacture of the substance
- Environmental release category (ERC):
- ERC1: Manufacture of the substance
- Name of activity / technique:
- Use in closed process, no likelihood of exposure
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in closed, continuous process with occasional controlled exposure
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in closed batch process (synthesis or formulation)
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in batch and other process (synthesis) where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or preparation into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Related assessment:
- use assessed in an own CSR
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Registration/ Notification status for the use:
- use registered according to REACH Article 10; total tonnage manufactured/imported >=10tonnes/year per registrant
- Use name:
- Formulation of lubricant additives
- Name of activity / technique:
- Formulation of lubricant additives
- Environmental release category (ERC):
- ERC2: Formulation into mixture
- Name of activity / technique:
- Use in closed process, no likelihood of exposure
- Process category (PROC):
- PROC 1: Chemical production or refinery in closed process without likelihood of exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in closed, continuous process with occasional controlled exposure
- Process category (PROC):
- PROC 2: Chemical production or refinery in closed continuous process with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in closed batch process (synthesis or formulation)
- Process category (PROC):
- PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
- Name of activity / technique:
- Use in batch and other process (synthesis) where opportunity for exposure arises
- Process category (PROC):
- PROC 4: Chemical production where opportunity for exposure arises
- Name of activity / technique:
- Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
- Process category (PROC):
- PROC 5: Mixing or blending in batch processes
- Name of activity / technique:
- Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
- Process category (PROC):
- PROC 8a: Transfer of substance or mixture (charging and discharging) at non-dedicated facilities
- Name of activity / technique:
- Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
- Process category (PROC):
- PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
- Name of activity / technique:
- Transfer of substance or preparation into small containers (dedicated filling line, including weighing)
- Process category (PROC):
- PROC 9: Transfer of substance or mixture into small containers (dedicated filling line, including weighing)
- Name of activity / technique:
- Use as laboratory agent
- Process category (PROC):
- PROC 15: Use as laboratory reagent
- Product category formulated:
- PC 17: Hydraulic fluids
- PC 24: Lubricants, greases, release products
- PC 25: Metal working fluids
- Substance supplied to that use in form of:
- as such
- Related assessment:
- use assessed in an own CSR
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
