Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 11 SEPTEMBER 2018 to 27 MAY 2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Title:
Unnamed
Year:
2019
Report date:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
OECD Guidelines for the Testing of Chemicals, Method No.104, adopted 23.mar.2006: "Vapour Pressure"
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell

Test material

Constituent 1
Chemical structure
Reference substance name:
1,4-bis(isopropylamino)anthraquinone
EC Number:
238-101-9
EC Name:
1,4-bis(isopropylamino)anthraquinone
Cas Number:
14233-37-5
Molecular formula:
C20H22N2O2
IUPAC Name:
1,4-bis(isopropylamino)anthraquinone
Test material form:
solid: particulate/powder

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#2
Temp.:
ca. 25 °C
Vapour pressure:
ca. 0 Pa
Key result
Test no.:
#1
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0 Pa

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the test item 1,4-bis(isopropylamino)anthraquinone was determined
at nine different temperatures (30 -150 °C) according to OECD 104 resp. EU A.4 using the
effusion method (weight loss). Experiment 1 - 6 (nominal temperature 30 - 105 °C) showed
no reproducible weight loss. When visible contaminations, caused by explosive evaporation
of the test item, were observed, the cells were meticulously cleaned and weighed. This
weight was used as initial weight for the subsequent measurements. To avoid bias, these
measurements were not used for calculations.
Three experiments could be evaluated as they showed relevant and reproducible weight
loss. All evaluated experiments showed good repeatability, giving relative standard deviations of less than 29 % (limit value from the guideline 30 %) and good correlation.
Therefore, the result of the test can be considered valid.